The Kristiina Mäkinen Lab
PLANT VIROLOGY
RECENT PUBLICATIONS
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Saha, S, Hafrén, A and Mäkinen, K. (2019) Dynamics of Protein Accumulation from the 3′ End of Viral RNA Are Different from Those in the Rest of the Genome in Potato Virus A Infection, J. Virol. 93:e00721-19. https://doi.org/10.1128/ JVI.00721-19.
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Eskelin, K, Varjosalo, M, Ravantti J, and Makinen, K (2019) Ribosome profiles and riboproteomes of healthy and Potato virus A- and Agrobacterium-infected Nicotiana benthamiana plants, Molecular Plant Pathology , vol. 20 , no. 3 , pp. 392-409. doi.org/10.1111/mpp.12764.
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De S, Chavez-Calvillo G, Wahlsten M, Mäkinen K. (2018) Disruption of the methionine cycle and reduced cellular glutathione levels underlie potex-potyvirus synergism in Nicotiana benthamiana. Mol Plant Pathol. 2018 Jan 24. doi: 10.1111/mpp.12661.
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Mäkinen, K., Lohmus, A. and Pollari, M. (2017) Plant RNA Regulatory Network and RNA Granules in Virus Infection, Frontiers in Plant Science 11 Dec, https://doi.org/10.3389/fpls.2017.02093
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De S., Lõhmus A., Pollari M., Saha S., and Mäkinen K. (2017) Host-Virus Interactions, from Potyvirus Replication to Translation, Plant Viruses Diversity, Interaction and Management (in press).
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Lõhmus A., Hafrén A., and Mäkinen K. (2017) Coat protein regulation by CK2, CPIP, HSP70 and CHIP is required for Potato virus A replication and coat protein accumulation, Journal of Virology, 91(3): e01316-16.
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Besong-Ndika, J., Wahlsten, M., Cardinale, D., Pille, J., Walter, J., Michon, T., and Mäkinen K. (2016)Towards the reconstitution of a two-enzyme cascade for resveratrol synthesis on potyvirus particles, Frontiers in Plant Sciences, 7:89. doi:10.3389/fpls.2016.00089.
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Lõhmus A., Varjosalo M., and Mäkinen K. (2015) Protein composition of 6K2-induced membrane structures formed during Potato virus A infection, Molecular Plant Pathology, doi: 10.1111/mpp.12341.
Ivanov, K.I., Eskelin, K., Bašić, M., De, S., Lõhmus, A., Varjosalo, M., and Mäkinen K. (2016) Molecular insights into the function of the viral RNA silencing suppressor HC-pro, The Plant Journal 85, 30–45
Hafren, A., Lõhmus, A, and Mäkinen, K. (2015) Formation of Potato virus A-induced RNA granules and viral translation are interrelated processes required for optimal virus accumulation, PLOS Pathogens, 11:e1005314. doi: 10.1371/journal.ppat.1005314.
Besong-Ndika, J., Ivanov, K.I., Hafrèn, A., Michon, T., and Mäkinen, K. (2015) Co-translational CP-mediated inhibition of potyviral RNA translation, Journal of Virology 89, 4237-4248.
Ivanov, K.I., Bašić, M, Varjosalo, M., and Mäkinen K. (2014) Efficient one-step purification of Twin-Strep-tagged proteins and their specific complexes on Strep-Tactin resin cross-linked with Bis(sulfosuccinimidyl) suberate (BS3), Journal of Visual Experiments (86), e51536.
Pille, J., Cardinale, D., Carette, N., Di Primo, C., Besong, J., Walter, J., Lecoq, H., van Eldijk, M.B., Smits, F.C.M., Schoffelen, S., Beekwilder, J., van Hest, J.C.M., Mäkinen, K. and Michon, T. (2013). A General Strategy for Ordered Non-covalent Protein Assembly on Well-defined Nano-scaffolds, Biomacromolecules 14, 4351-4359.
Hafren, A., Eskelin, K., and Mäkinen K. (2013) Ribosomal protein P0 promotes Potato virus A infection and functions in viral translation together with VPg and eIF(iso)4E, Journal of Virology, 87, 4302–4312.
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PhD THESES
​2016 Besong-Ndika, Jane (University of Helsinki & University of Bordeaux)
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2010 Hafrén, Anders (University of Helsinki)
The viral coat protein is regulated by HSP70 and HSP40 in Potato virus A infection
2010 Rantalainen, Kimmo (University of Helsinki)
Biochemical and structural properties of Potato virus A VPg
2008 Kelloniemi, Jani (University of Helsinki)
Potato virus A as a heterologous protein expression tool in plants
Co-supervision with Prof. Jari Valkonen
2007 Gabrenaite-Verkhovskaya, Rasa (University of Helsinki)
Movement-associated proteins of Potato virus A: attachment to virus particles and phosphorylation
2006 Mäkeläinen, Katri (Univeristy of Helsinki)
Lost in Translation: Translation Mechanisms in Production of Cocksfoot Mottle Virus Proteins
2005 Puustinen, Pietri (University of Helsinki)
Posttranslational modifications of potato virus A movement related proteins CP and VPg